解剖学和形态学
麻醉学
听力与言语-语言病理学
行为科学
心脏和心血管系统
细胞和组织工程学
临床神经病学
危重症监护医学
牙科,口腔外科和医学
皮肤病学
急诊医学
内分泌学和新陈代谢
肠胃学和肝脏学
老人病学和老年医学
卫生保健科学和服务
血液学
免疫学
传染病
综合和补充性医学
医学伦理学
医学信息学
医学实验室技术
医学,全科和内科
医学,法律
医学,研究和试验
神经系统科学
护理
营养学和饮食学
产科医学和妇科医学
肿瘤学
眼科学
整形外科学
耳鼻喉科学
病理学
儿科学
周围血管疾病
药理学和药剂学
生理学
基本医疗保健
精神病学
公共、环境和职业卫生
放射学,核医学和医学成像
康复学
生殖生物学
呼吸系统
风湿病学
运动科学
外科学
毒理学
热带医学
泌尿学和肾脏学
病毒学
老年医学
健康政策和服务
心理学,临床
abstract::Two new xanthones, caledonixanthone M 1 and caloxanthone L 2, and one new acid, caledonic acid 6 were isolated from the hexane-soluble extract of the stem bark of Calophyllum caledonicum. In the course of this phytochemical study, seven other known compounds - calothwaitesixanthone, calozeyloxanthone, allanxanthone, i...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2003-818004
更新日期:2003-12-01 00:00:00
abstract::The antihyperglycemic action of andrographolide, an active principle in the leaves of Andrographis paniculata (Burm. f.) Nees, was investigated in streptozotocin-induced diabetic rats (STZ-diabetic rats). Oral treatment of andrographolide decreased the plasma glucose concentrations of STZ-diabetic rats in a dose-depen...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2003-45185
更新日期:2003-12-01 00:00:00
abstract::Four p-terphenyl derivatives named curtisians I-L (1-4) were isolated from the MeOH extract of the fruit bodies of Paxillus curtisii. Their structures were elucidated by 2D NMR, MS, IR and UV spectroscopy and chemical reaction. The absolute configurations of curtisians were determined by GC-MS on a chiral column of th...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2003-45159
更新日期:2003-11-01 00:00:00
abstract::Transformed root cultures of ipecac (Cephaelis ipecacuanha A. Richard), one of the recalcitrant woody plant species for Agrobacterium-mediated transformation, were established by co-culturing of in vitro petiole segments with Agrobacterium rhizogenes ATCC 15 834. Southern blot analysis of the established roots reveale...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2003-45149
更新日期:2003-11-01 00:00:00
abstract::In the present study, we demonstrate that saucernetin-8 ( 1) and saucernetin-7 ( 2), isolated from the underground parts of Saururus chinensis (Saururaceae), exerted potent inhibitory effects on LPS-induced nitric oxide (NO) and prostaglandin E (2) (PGE (2)) production in RAW 264.7 cells. Both compounds 1 and 2, known...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2003-45106
更新日期:2003-10-01 00:00:00
abstract::Three compounds with anti-inflammatory activity were isolated from Schinus molle fruits. Two of the compounds were identified as 3- epi-isomasticadienolalic acid ( 1), isomasticadienonalic acid ( 2) and chamaejasmin ( 3). Triterpenes 1 and 2, and biflavanone 3 were tested on two models of mice paw inflammation: one of...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2003-45096
更新日期:2003-10-01 00:00:00
abstract::A new indole alkaloid, galanthindole, was isolated from Galanthus plicatus ssp. byzantinus (Amaryllidaceae), a plant native to northwestern Turkey. Incorporating a non-fused indole ring, galanthindole may represent the prototype of a new subgroup of the Amaryllidaceae alkaloids. Two other bases, (+)-11-hydroxyvittatin...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2003-43206
更新日期:2003-09-01 00:00:00
abstract::Six new pyrrolizidine alkaloids, a new carboxylic acid, a new phenolic and a new oleanane glycoside, together with the known compounds 7,7'-bis-(4-hydroxy-3,5-dimethoxyphenyl)-8,8'-dihydroxymethyltetrahydrofuran 4'-O-beta-D-glucopyranoside, rosmarinic acid, caffeic acid, tormentic acid 28-O-beta- D-glucopyranoside, eu...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2003-43202
更新日期:2003-09-01 00:00:00
abstract::The dichloromethane-soluble fraction of the methanol extract of the stem bark of Millettia versicolor Welw. (Leguminosae) has been shown to possess anti-inflammatory activity. The chromatographic fractionation and subsequent analysis of the spectroscopic data of this extract led to the isolation and identification of ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2003-42794
更新日期:2003-08-01 00:00:00
abstract::The anti-inflammatory activity of alpha-viniferin, a trimer of resveratrol, has been demonstrated in an animal model of carrageenin-induced paw edema, and inhibitory effects of the compound on cyclooxygenase (COX) and inducible nitric oxide synthase (iNOS) have been investigated in order to understand the mode of the ...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2003-42787
更新日期:2003-08-01 00:00:00
abstract::In an attempt to induce positive effects on the acclimatization of in vitro propagated Echinacea pallida, four arbuscular mycorrhizal (AM) fungi, Glomus mosseae, Gigaspora ramisporophora, Scutellospora fulgida and Entrophospora colombiana were selected to aid the soil adaptation process. Fungal inocula affected the su...
journal_title:Planta medica
pub_type: 信件
doi:10.1055/s-2003-41124
更新日期:2003-07-01 00:00:00
abstract::It has been reported that cedarwood oil has sedative effects when inhaled. In this study, we evaluated sedative effects of inhaled cedrol, which is a major component of cedarwood oil. Accumulative spontaneous motor activity was significantly decreased in the cedrol-exposed Wistar rats. Similar results were confirmed i...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2003-41114
更新日期:2003-07-01 00:00:00
abstract::Based on rDNA ITS sequences of D. officinale and the other 37 species of Dendrobium, a pair of allele-specific diagnostic primers, TP-JB01S and TP-JB01X, were designed to authenticate D. officinale from the other species. Before the diagnostic PCR, the primer pair, P1 and P2, for amplifying the whole ITS region was us...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2003-40651
更新日期:2003-06-01 00:00:00
abstract::Gleditsioside E, a triterpene saponin isolated from Gleditsia sinensis, showed significant cytotoxicity against Bel-7402, BGC-823, HeLa, HL-60 and MCF-7 cell lines. The results of flow cytometry with annexin V-FITC/PI double staining proved that gleditsioside E mainly induced early apoptosis in HL-60 cells. Gleditsios...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2003-40645
更新日期:2003-06-01 00:00:00
abstract::Baicalein, berberine, curcumin and hesperidin are the major components derived from Scutellaria baicalensis, Coptis japonica, Curcuma longa and Poncirus trifoliata, respectively. These plants have been used for the treatment of diverse chronic inflammatory diseases including respiratory disease in oriental medicine an...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2003-40655
更新日期:2003-06-01 00:00:00
abstract::A micellar electrokinetic capillary chromatography (MEKC) method for the determination of xanthyletin and xanthoxyletin in the roots bark of three Citrus plants was developed for the first time. The electrophoresis buffer was 10 mmol/L sodium borate containing 50 mmol/L sodium dodecyl sulfate, 20% (v/v) acetonitrile a...
journal_title:Planta medica
pub_type: 信件
doi:10.1055/s-2003-39697
更新日期:2003-05-01 00:00:00
abstract::The methanolic extract of the fruits of Torilis japonica showed a potent inhibition against 5 alpha-reductase activity in vitro. Bioassay-guided fractionation of the methanol extract of the fruits followed by repeated silica gel chromatography led to the isolation of an active principle and its structure was identifie...
journal_title:Planta medica
pub_type: 信件
doi:10.1055/s-2003-39717
更新日期:2003-05-01 00:00:00
abstract::We have isolated five furanocoumarins, byakangelicin, phellopterin, imperatorin, isoimperatorin, and oxypeucedanin methanolate, from the roots of Angelica dahurica (Umbelliferae) and prepared five semi-synthesized compounds by the partial reduction of each isolated furanocoumarin, and the effects of these compounds on...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2003-39702
更新日期:2003-05-01 00:00:00
abstract::Ent-11alpha-hydroxy-16-kauren-15-one (1) induced apoptosis in a human leukemia cell line (HL-60 cells), however, the apoptosis-inducing properties of 1 and its related compounds remain to be proved. We examined the involvement of caspases, a family of cysteine aspartic proteases, which play a central role in induction...
journal_title:Planta medica
pub_type: 信件
doi:10.1055/s-2003-38888
更新日期:2003-04-01 00:00:00
abstract::The present study investigated the role of adenosine in the stimulatory action of paeoniflorin on in vitro glucose transport. Paeoniflorin increased the uptake of a radiolabeled, non-metabolizable glucose derivative into isolated white adipocytes of Wistar rat in a concentration-dependent manner and this action was ab...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2003-38878
更新日期:2003-04-01 00:00:00
abstract::3beta-Acetoxy-17beta-hydroxy-androst-5-ene was isolated from aerial parts of Acacia nilotica (L.) Willd (Mimosaceae). The structure of this compound was established by spectral analysis and single crystal X-ray diffraction analysis. The steroid showed dose-dependent anti-inflammatory activity against TPA-induced mouse...
journal_title:Planta medica
pub_type: 信件
doi:10.1055/s-2003-38482
更新日期:2003-03-01 00:00:00
abstract::The new diterpenoids, candesalvoquinone, 12- O-methylcandesalvone B, candesalvone B methyl ester with the 3,4-secoabietane skeleton, and candelabroquinone with the abietane skeleton were isolated from the aerial parts of Salvia candelabrum, together with the known compound candelabrone. The structures were established...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2003-38484
更新日期:2003-03-01 00:00:00
abstract::High molecular compounds from Chinese herbal medicines, including ribosome-inactivating proteins and polysaccharides from both fungi and high plants have been tested for the treatment of malignant diseases. Polysaccharides possessing immunostimulating activities can be used as adjuvants in tumor treatment. The fungi c...
journal_title:Planta medica
pub_type: 杂志文章,评审
doi:10.1055/s-2003-38494
更新日期:2003-03-01 00:00:00
abstract::The activity-guided fractionation of the hydroalcoholic extract of trunk bark of Cedrelopsis grevei led to the isolation of five coumarins, norbraylin (1), methyl-O-cedrelopsin (2), cedrecoumarin A (3), scoparone (4) and braylin (5) as a part of the constituents responsible for the vasorelaxing activity observed for t...
journal_title:Planta medica
pub_type: 信件
doi:10.1055/s-2003-37717
更新日期:2003-02-01 00:00:00
abstract::Two new protopine-type alkaloids, argemexicaine A (1) and argemexicaine B (2), along with thirteen known alkaloids, were isolated from MeOH extracts of Formosan Argemone mexicana L. (Papaveraceae). Physical and spectral analyses, particularly IR and thermo-modulated 1D and 2D NMR, were used to determine the transannul...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2003-37710
更新日期:2003-02-01 00:00:00
abstract::An in vitro propagation protocol for rapidly producing Hydrastis canadensis L., Goldenseal, plantlets from disk tissue of young leaves was developed. Leaf explants were inoculated on MS medium supplemented with various concentrations of NAA and TDZ for production of callus. Two-month-old calli were sub-cultured on MS ...
journal_title:Planta medica
pub_type: 信件
doi:10.1055/s-2003-37039
更新日期:2003-01-01 00:00:00
abstract::Bamboo, Phyllostachys edulis produces well known edible shoots in Asia. Immunostimulating anticomplementary (complement activating) substances have been recognized as a characteristic biological response modifier (BRM). In the present study, we isolated and characterized three anticomplementary beta-glucans (BS-BGA, B...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2003-37038
更新日期:2003-01-01 00:00:00
abstract::A callus culture of Aleurites fordii Hemsley (Euphorbiaceae) producing five galloylglucoses and an ellagitannin, geraniin, was established. The production of pentagalloylglucose was remarkably enhanced under light irradiation compared with that in the dark. Cell growth and tannin production were also greatly affected ...
journal_title:Planta medica
pub_type: 信件
doi:10.1055/s-2002-36348
更新日期:2002-12-01 00:00:00
abstract::Catharanthus roseus cell suspension cultures were employed for the biotransformation of 2alpha,5alpha,10beta,14beta-tetraacetoxy-4(20),11-taxadiene ( 1), and four metabolites were obtained. Based on their physical and chemical data, the structures of the four metabolites were respectively elucidated as 10beta-hydroxy-...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2002-36340
更新日期:2002-12-01 00:00:00
abstract::Three flavonoids: norwogonin, dihydronorwogonin and baicalein, were isolated from the roots of Scutellaria baicalensis, as potential inhibitors of VHR dual-specificity protein tyrosine phosphatase (DS-PTPase). Norwogonin (IC 50 = 1.1 microM), dihydronorwogonin (IC 50 = 2.9 microM) and baicalein (IC 50 = 2.4 microM) sh...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2002-36351
更新日期:2002-12-01 00:00:00
abstract::Purification of a cytotoxic crude alkaloid extract of Cassytha filiformis led to the isolation of four known aporphine alkaloids: neolitsine, dicentrine, cassythine (= cassyfiline) and actinodaphnine. Their structures were determined by analysis of spectroscopic data. All isolated alkaloids were tested for their cytot...
journal_title:Planta medica
pub_type: 信件
doi:10.1055/s-2002-35651
更新日期:2002-11-01 00:00:00
abstract::Effects of puerarin, an active principle contained in the roots of Pueraria lobata (Leguminosae), on the regulation of glucose metabolism in an insulin deficient state were investigated in cultured myoblast C 2 C 12 cells using glucose uptake as indicator. Puerarin enhanced the uptake of radioactive glucose into C 2 C...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2002-35656
更新日期:2002-11-01 00:00:00
abstract::Chemical investigation of the EtOH extract of Morus alba L. (Moraceae), as guided by free radical scavenging activity, furnished 5,7-dihydroxycoumarin 7-methyl ether (1), two prenylflavones, cudraflavone B (2) and cudraflavone C (3), and oxyresveratrol (4). Compounds 1 and 4 showed superoxide scavenging effects with t...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2002-34930
更新日期:2002-10-01 00:00:00
abstract::Many anti-inflammatory agents are known to significantly enhance the terminal differentiation of some cancer cells such as leukemia cells. In this study, the effect of yomogin, a eudesmane sesquiterpene lactone isolated from Artemisia princeps with anti-inflammatory activity, was investigated in human promyelocytic le...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2002-34937
更新日期:2002-10-01 00:00:00
abstract::Five known abietane diterpenes, fatty acid esters of 7alpha-acyloxy-6beta-hydroxyroyleanone (1), grandidone A (2), 7alpha-acetoxy-6beta-hydroxyroyleanone (3), 6beta,7alpha-dihydroxyroyleanone (4), and coleon U (5), isolated from Plectranthus grandidentatus Gürke, were evaluated for their in vitro antiproliferative act...
journal_title:Planta medica
pub_type: 信件
doi:10.1055/s-2002-34407
更新日期:2002-09-01 00:00:00
abstract::Jujuboside A (JuA) is a glycoside extracted from the seed of Ziziphus jujuba Mill var. spinosa (Bunge) Hu ex H F Chou, a Chinese herbal medicine, which has long been known as a sedative-hypnotic drug. The present study used the method of intracerebroventricular (i.c.v.) JuA in vivo to detect the effect of JuA on paire...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2002-34398
更新日期:2002-09-01 00:00:00
abstract::The absolute stereostructure of a novel skeletal diterpene, standishinal (1), from the bark of Thuja standishii was confirmed by X-ray crystallographic analyses of 1 and its p-bromobenzoate derivative. Aromatase inhibitory activities of standishinal, eight known diterpenes, totarol, 12-methoxyabieta-8,11,13-trien-11-o...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2002-33787
更新日期:2002-08-01 00:00:00
abstract::Recently, we showed that intravenous (i.v.) treatment with the essential oil of Mentha x villosa (EOMV) in pentobarbitone-anaesthetised rats decreased blood pressure; the effect occurred independently of the presence of an operational central autonomic drive to the cardiovascular system. This finding suggested that th...
journal_title:Planta medica
pub_type: 杂志文章
doi:10.1055/s-2002-33797
更新日期:2002-08-01 00:00:00
abstract::Three new pyrone glucosidic derivatives, together with the known pyromeconic acid glucoside, three acytelenes and two eudesmanes, were obtained from the aerial parts of Conyza albida. The structures were elucidated by high field NMR spectroscopy. ...
journal_title:Planta medica
pub_type: 信件
doi:10.1055/s-2002-32895
更新日期:2002-07-01 00:00:00
abstract::The seed pods of Erythrina latissima yielded erysotrine, erysodine, syringaresinol, vanillic acid, a new erythrina alkaloid, (+)-10,11-dioxoerysotrine, which was lethal to brine shrimp and 2-(5'-hydroxy-3'-methoxy phenyl)-6-hydroxy-5-methoxybenzofuran, which showed strong antimicrobial activity against the yeast spore...
journal_title:Planta medica
pub_type: 信件
doi:10.1055/s-2002-32891
更新日期:2002-07-01 00:00:00